NIH Mouse Imaging Facility - a multi-modal preclinical animal imaging facility open to the NIH intramural research community

Authors

• BA Klaunberg
• MJ Lizak
• HD Morris
• JP Munasinghe
• DJ DesPres
• VM Diaz
• DR Donahue

Abstract

The NIH Mouse Imaging Facility (MIF) is a shared, intramural resource that provides the NIH intramural community access to state-of-the-art modern medical imaging equipment and techniques optimized for small animal imaging studies. The MIF is open to all NIH intramural investigators to use preclinical medical imaging as a tool to further their research. The MIF is administered by NINDS, and the MIF Subcommittee of the NMR Center Steering Committee provides oversight for MIF activities. The MIF currently offers the following medical imaging modalities: - High resolution magnetic resonance imaging (MRI) for in-vivo and ex-vivo studies, - High resolution micro X-ray computed tomography (Micro-CT) for in-vivo and ex-vivo studies, - High resolution ultrasound imaging with color flow Doppler and photoacoustic optical imaging capability, - Optical imaging that includes Bioluminescence and Fluorescence. Radiographic co-registration is available, as well as the MARS Multimodal Animal Rotation System for semi-3D optical imaging. The MIF supports the imaging of mice, rats, non-human primates and other animal models. Complimentary to imaging studies, MIF can also measure systemic blood pressure, pulse oximetry, and electrocardiogram (ECG). Imaging results from the various imaging modalities and equipment supported in the MIF are presented as an overview of the available resources.

Scientific Focus Area: Research Support Services

This page was last updated on Friday, March 26, 2021